# Statistical Challenges Arising from Genome Resequencing

Created: | 2010-07-13 18:15 |
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Institution: | Isaac Newton Institute for Mathematical Sciences |

Description: | The current generation of high-throughput genetic and genomic platforms, has had a great impact on biomedical research, and given new impetus to studies of molecular mechanisms of genetic disease, and to systems biology. The next big technological step forward is the advent of cheap, fast, sequencing platforms that will allow near-complete genome sequences to be quickly and affordably obtained from individual members of any species. Individual genomes from humans, their pathogens and model organisms will have an enormous impact on population genetics and evolutionary theory, as well as on epidemiology, particularly our understanding of infectious disease.
Read more at: http://www.newton.ac.uk/programmes/CGR/index.html |

# Media items

This collection contains 20 media items.

### Media items

#### A statistical framework for the analysis of ChIP-Seq data

Gottardo, R (University of British Columbia)

Friday 16 July 2010, 11:30-12:00

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Tue 20 Jul 2010

#### Allele specific expression analysis using high throughput DNA sequencing

Plagnol, V (University College London)

Friday 16 July 2010, 10:00-10:30

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Tue 20 Jul 2010

#### Analysis of whole cancer genomes

Campbell, P (Wellcome Trust Sanger Institute)

Wednesday 14 July 2010, 16:00-16:30

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Thu 15 Jul 2010

#### Calling small indels in the 1000 Genomes low-coverage and high-coverage pilots

Albers, C A (Cambridge)

Wednesday 14 July 2010, 09:00-09:30

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Wed 14 Jul 2010

#### Cis-regulatory SNPs (cis-rSNPs) altering transcription detected by allelic expression (AE) mapping

Pastinen, T (McGill University)

Friday 16 July 2010, 09:30-10:00

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Tue 20 Jul 2010

#### Deconvolving the epigenome: analysis strategies for genome-wide studies

Down, T (University of Cambridge)

Wednesday 14 July 2010, 17:00-17:30

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Thu 15 Jul 2010

#### Efficient construction of overlap assemblies using suffix array based methods

Durbin, R (Wellcome Trust Sanger Institute)

Wednesday 14 July 2010, 09:30-10:00

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Wed 14 Jul 2010

#### Genome-wide characteristics of sequence coverage by next-generation sequencing: how does this impact interpretation?

Taylor, J (CSIRO)

Friday 16 July 2010, 10:30-11:00

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Tue 20 Jul 2010

#### Genotype imputation with thousands of genomes

Marchini, J (University of Oxford)

Wednesday 14 July 2010, 11:00-11:30

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Thu 15 Jul 2010

#### Identification of enriched regions in ChIP-seq and whole-genome sequencing data

Park, P (Harvard University)

Friday 16 July 2010, 12:30-13:00

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Tue 20 Jul 2010

#### Microevolutionary analysis of metagenomic data

Falush, D (University College Cork)

Thursday 15 July 2010, 16:30-17:00

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Tue 20 Jul 2010

#### Panel Discussion Session

Panel Discussion Session

Tuesday 03 August 2010, 17:15-18:15

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Mon 9 Aug 2010

#### Phasing SNPs and sequences

Kong, A (DeCode genetics)

Wednesday 14 July 2010, 12:00-12:30

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Thu 15 Jul 2010

#### Prospects for pharmacogenetics in a genome-sequencing era

Nelson, M (GlaxoSmithKline)

Tuesday 03 August 2010, 15:20-16:00

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Mon 9 Aug 2010

#### Reference-free analysis of genetic variation

Iqbal, Z (University of Oxford)

Wednesday 14 July 2010, 10:00-10:30

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Wed 14 Jul 2010

#### Should I sequence my genome now?

Bentley, D (Illumina)

Tuesday 03 August 2010, 14:00-14:40

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Mon 9 Aug 2010

#### Species specific transcription in mice carrying human chromosome 21

Odom, D (University of Cambridge)

Friday 16 July 2010, 12:00-12:30

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Tue 20 Jul 2010

#### Statistical models for inference of SNVs in cancer genomes

Shah, SP (BCCRC)

Wednesday 14 July 2010, 16:30-17:00

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Thu 15 Jul 2010

#### The 1000 Genomes Project and challenges in population-scale sequencing

McVean, G (Oxford)

Tuesday 03 August 2010, 16:30-17:15

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Mon 9 Aug 2010

#### Understanding variation in mRNA processing with RNA sequencing

Pickrell, J (University of Chicago)

Thursday 15 July 2010, 09:00-09:30

**Collection**:
Statistical Challenges Arising from Genome Resequencing

**Institution**:
Isaac Newton Institute for Mathematical Sciences

**Created**:
Fri 16 Jul 2010